Medicine is science, finding the right vehicle to disseminate the contents of this science is art. Several successful medical TV series such as “ER” and “House” have proven that medicine is full of ability for entertaining, contrary to the common perception. The medical community has already used video games and virtue reality technology for medical training, psychotherapy and patient education with positive outcomes. However, creating a successful medical game targeting the general public is a very challenging job that requires devoted medical professionals and experienced IT game designers working in synergy. Taking advantage of our existing network of hospitals and medical experts, we are currently working on several preliminary ideas for developing medical-edutainment games. We believe, given the power of combining entertainment and scientific knowledge, this will be a promising approach to explain the mysteries of human life to children and their parents.